Loretta Lazzarato: search on Z-Library

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1

Synthesis of NO-Donor Bisphosphonates and Their in-Vitro Action on Bone Resorption

Lazzarato, Loretta, Rolando, Barbara, Lolli, Marco L., Tron, Gian Cesare, Fruttero, Roberta, Gasco, Alberto, Deleide, Guido, Guenther, Harald L.

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 134 KB

english, 2005

2

Nitrooxymethyl-Substituted Analogues of Celecoxib: Synthesis and Pharmacological Characterization

Donatella Boschi, Loretta Lazzarato, Barbara Rolando, Andrea Filieri, Clara Cena, Antonella Di Stilo, Roberta Fruttero, Alberto Gasco

Journal:

Chemistry & Biodiversity

Year:

2009

Language:

english

File:

PDF, 198 KB

english, 2009

3

A Molecular Hybrid for Mitochondria-Targeted NO Photodelivery

Sortino, Salvatore, sodano, federica, gazzano, elena, fraix, aurore, rolando, barbara, lazzarato, loretta, russo, marina, blangetti, marco, riganti, chiara, fruttero, roberta, gasco, alberto

Journal:

Year:

2017

Language:

english

File:

PDF, 1.95 MB

english, 2017

4

Development of a New Class of Potential Antiatherosclerosis Agents: NO-Donor Antioxidants.

Clara Cena, Donatella Boschi, Gian Cesare Tron, Kostantin Chegaev, Loretta Lazzarato, Antonella Di Stilo, Manuela Aragno, Roberta Fruttero, Alberto Gasco

Journal:

Year:

2005

File:

PDF, 15 KB

2005

5

Development of a new class of potential antiatherosclerosis agents: NO-donor antioxidants

Clara Cena, Donatella Boschi, Gian Cesare Tron, Kostantin Chegaev, Loretta Lazzarato, Antonella Di Stilo, Manuela Aragno, Roberta Fruttero, Alberto Gasco

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 274 KB

english, 2004

6

Designing Multitarget Anti-inflammatory Agents: Chemical Modulation of the Lumiracoxib Structure toward Dual Thromboxane Antagonists–COX-2 Inhibitors

Prof. Dr. Massimo Bertinaria, Dr. Mohammed Abrar Abdul Gaffar Shaikh, Dr. Carola Buccellati, Prof. Dr. Clara Cena, Dr. Barbara Rolando, Dr. Loretta Lazzarato, Prof. Roberta Fruttero, Prof. Alberto Gas

Journal:

Year:

2012

Language:

english

File:

PDF, 588 KB

english, 2012

7

Nitric Oxide Donor Doxorubicins Accumulate into Doxorubicin-Resistant Human Colon Cancer Cells Inducing Cytotoxicity

Chegaev, Konstantin, Riganti, Chiara, Lazzarato, Loretta, Rolando, Barbara, Guglielmo, Stefano, Campia, Ivana, Fruttero, Roberta, Bosia, Amalia, Gasco, Alberto

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.38 MB

english, 2011

8

H 2 S-Donating Doxorubicins May Overcome Cardiotoxicity and Multidrug Resistance

Chegaev, Konstantin, Rolando, Barbara, Cortese, Daniela, Gazzano, Elena, Buondonno, Ilaria, Lazzarato, Loretta, Fanelli, Marilù, Hattinger, Claudia M., Serra, Massimo, Riganti, Chiara, Fruttero, Rober

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 2.30 MB

english, 2016

9

Light-Tunable Generation of Singlet Oxygen and Nitric Oxide with a Bichromophoric Molecular Hybrid: a Bimodal Approach to Killing Cancer Cells

Fraix, Aurore, Blangetti, Marco, Guglielmo, Stefano, Lazzarato, Loretta, Marino, Nino, Cardile, Venera, Graziano, Adriana C. E., Manet, Ilse, Fruttero, Roberta, Gasco, Alberto, Sortino, Salvatore

Journal:

Year:

2016

Language:

english

File:

PDF, 2.15 MB

english, 2016

10

NO release regulated by doxorubicin as green light-harvesting antenna

Fraix, Aurore, Parisi, Cristina, Failla, Mariacristina, Chegaev, Konstantin, Spyrakis, Francesca, Lazzarato, Loretta, Fruttero, Roberta, Gasco, A, Sortino, Salvatore

Journal:

Chemical Communications

Year:

2020

File:

PDF, 1.33 MB

2020

11

Improvement of conventional anti-cancer drugs as new tools against multidrug resistant tumors

Dallavalle, Sabrina, DobriÄiÄ, Vladimir, Lazzarato, Loretta, Gazzano, Elena, Machuqueiro, Miguel, Pajeva, Ilza, Tsakovska, Ivanka, Zidar, Nace, Fruttero, Roberta

Journal:

Drug Resistance Updates

Year:

2020

File:

PDF, 2.61 MB

2020

12

Mechanistic Insights into Cyclooxygenase Irreversible Inactivation by Aspirin

Paolo Tosco, Loretta Lazzarato

Journal:

Year:

2009

Language:

english

File:

PDF, 558 KB

english, 2009

13

The Furoxan System: Design of Selective Nitric Oxide (NO) Donor Inhibitors of COX-2 Endowed with Anti-Aggregatory and Vasodilating Activities

Erika Del Grosso, Donatella Boschi, Loretta Lazzarato, Clara Cena, Antonella Di Stilo, Roberta Fruttero, Stefano Moro, Alberto Gasco

Journal:

Chemistry & Biodiversity

Year:

2005

Language:

english

File:

PDF, 330 KB

english, 2005

14

A New Class of Ibuprofen Derivatives with Reduced Gastrotoxicity

Lolli, Marco L., Cena, Clara, Medana, Claudio, Lazzarato, Loretta, Morini, Giuseppina, Coruzzi, Gabriella, Manarini, Stefano, Fruttero, Roberta, Gasco, Alberto

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 73 KB

english, 2001

15

Corrigendum: Designing Multitarget Anti-inflammatory Agents: Chemical Modulation of the Lumiracoxib Structure toward Dual Thromboxane Antagonists-COX-2 Inhibitors

Bertinaria, Massimo, Shaikh, Mohammed Abrar Abdul Gaffar, Buccellati, Carola, Cena, Clara, Rolando, Barbara, Lazzarato, Loretta, Fruttero, Roberta, Gasco, Alberto, Hoxha, Malvina, Capra, Valérie, Sala

Journal:

Year:

2012

File:

PDF, 126 KB

2012

16

Synthesis of Some Novel Organic Nitrates and Comparative in Vitro Study of Their Vasodilator Profile

Chegaev, Konstantin, Lazzarato, Loretta, Marcarino, Paolo, Di Stilo, Antonella, Fruttero, Roberta, Vanthuyne, Nicolas, Roussel, Christian, Gasco, Alberto

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 206 KB

english, 2009

17

Furoxan Nitric Oxide Donors Disperse Pseudomonas aeruginosa Biofilms, Accelerate Growth, and Repress Pyoverdine Production

Poh, Wee Han, Barraud, Nicolas, Guglielmo, Stefano, Lazzarato, Loretta, Rolando, Barbara, Fruttero, Roberta, Rice, Scott A.

Journal:

ACS Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1.83 MB

english, 2017

18

Methotrexate-Loaded Solid Lipid Nanoparticles: Protein Functionalization to Improve Brain Biodistribution

Muntoni, Elisabetta, Martina, Katia, Marini, Elisabetta, Giorgis, Marta, Lazzarato, Loretta, Salaroglio, Iris, Riganti, Chiara, Lanotte, Michele, Battaglia, Luigi

Journal:

Year:

2019

Language:

english

File:

PDF, 944 KB

english, 2019

19

Fluorescent Nitric Oxide Photodonors Based on BODIPY and Rhodamine Antennae

Sortino, Salvatore, Parisi, Cristina, Failla, Mariacristina, Fraix, Aurore, Rolando, Barbara, Giaquinto, Eleonora, Spyrakis, Francesca, Gazzano, Elena, Riganti, Chiara, Lazzarato, Loretta, Fruttero, R

Journal:

Chemistry - A European Journal

Year:

2019

Language:

english

File:

PDF, 1.42 MB

english, 2019

20

Synthesis and preliminary biological profile of new NO-donor tolbutamide analogues

Yasinalli Tamboli, Loretta Lazzarato, Elisabetta Marini, Stefano Guglielmo, Michela Novelli, Pascale Beffy, Pellegrino Masiello, Roberta Fruttero, Alberto Gasco

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 262 KB

english, 2012

21

Furazan and furoxan sulfonamides are strong α-carbonic anhydrase inhibitors and potential antiglaucoma agents

Chegaev, Konstantin, Lazzarato, Loretta, Tamboli, Yasinalli, Boschi, Donatella, Blangetti, Marco, Scozzafava, Andrea, Carta, Fabrizio, Masini, Emanuela, Fruttero, Roberta, Supuran, Claudiu T., Gasco,

Journal:

Bioorganic & Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.37 MB

english, 2014

22

NO-Donor COX-2 Inhibitors. New Nitrooxy-Substituted 1,5-Diarylimidazoles Endowed with COX-2 Inhibitory and Vasodilator Properties

Chegaev, Konstantin, Lazzarato, Loretta, Tosco, Paolo, Cena, Clara, Marini, Elisabetta, Rolando, Barbara, Carrupt, Pierre-Alain, Fruttero, Roberta, Gasco, Alberto

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 244 KB

english, 2007

23

New furoxan derivatives for the treatment of ocular hypertension

Blangetti, Marco, Rolando, Barbara, Chegaev, Konstantin, Guglielmo, Stefano, Lazzarato, Loretta, Durante, Mariaconcetta, Masini, Emanuela, Almirante, Nicoletta, Bastia, Elena, Impagnatiello, Francesco

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 880 KB

english, 2017

24

Nitrooxyacyl Derivatives of Salicylic Acid: Aspirin-Like Molecules that Covalently Inactivate Cyclooxygenase-1

Prof. Dr. Clara Cena, Dr. Paolo Tosco, Dr. Elisabetta Marini, Dr. Loretta Lazzarato, Prof. Dr. Marco Piccinini, Dr. Cristina Ramondetti, Dr. Elisa Lupino, Prof. Roberta Fruttero, Prof. Alberto Gasco

Journal:

Year:

2011

Language:

english

File:

PDF, 672 KB

english, 2011

25

NO-Donor Phenols: A New Class of Products Endowed with Antioxidant and Vasodilator Properties

Boschi, Donatella, Tron, Gian Cesare, Lazzarato, Loretta, Chegaev, Konstantin, Cena, Clara, Di Stilo, Antonella, Giorgis, Marta, Bertinaria, Massimo, Fruttero, Roberta, Gasco, Alberto

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 366 KB

english, 2006

26

Searching for new NO-donor aspirin-like molecules: Furoxanylacyl derivatives of salicylic acid and related furazans

Loretta Lazzarato, Clara Cena, Barbara Rolando, Elisabetta Marini, Marco Lucio Lolli, Stefano Guglielmo, Elena Guaita, Giuseppina Morini, Gabriella Coruzzi, Roberta Fruttero, Alberto Gasco

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 324 KB

english, 2011

27

SAR Studies on Tetrahydroisoquinoline Derivatives: [4’-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-ylmethyl)biphenyl-4-ol] (MC70 1 ) Conjugated Through Flexible Alkyl Chains with Furazan Moieties Gives Rise to Potent and Selective Ligands of P-glycoprotein.

Guglielmo, Stefano, Lazzarato, Loretta, Contino, Marialessandra, Perrone, Maria Grazia, Chegaev, Konstantin, Carrieri, Antonio, Fruttero, Roberta, Colabufo, Nicola A., Gasco, Alberto

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 755 KB

english, 2016

28

Physicochemical profile and in vitro permeation behavior of a new class of non-steroidal anti-inflammatory drug candidates

Barbara Rolando, Loretta Lazzarato, Antonella Di Stilo, Roberta Fruttero, Pierre-Alain Carrupt, Sophie Martel, Alberto Gasco

Journal:

European Journal of Pharmaceutical Sciences

Year:

2010

Language:

english

File:

PDF, 312 KB

english, 2010

29

Paracetamol-Galactose Conjugate: A Novel Pro-drug for an Old Analgesic Drug.

Sodano, Dr. Federica, Lazzarato, Loretta, Rolando, Barbara, Spyrakis, Francesca, De Caro, Carmen, Magliocca, Salvatore, Marabello, Domenica, Chegaev, Konstantin, Gazzano, Elena, Riganti, Chiara, Calig

Journal:

Molecular Pharmaceutics

Year:

2019

Language:

english

File:

PDF, 888 KB

english, 2019

30

(Nitrooxyacyloxy)methyl Esters of Aspirin as Novel Nitric Oxide Releasing Aspirins

Lazzarato, Loretta, Donnola, Monica, Rolando, Barbara, Chegaev, Konstantin, Marini, Elisabetta, Cena, Clara, Di Stilo, Antonella, Fruttero, Roberta, Biondi, Stefano, Ongini, Ennio, Gasco, Alberto

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 1.34 MB

english, 2009

31

Enhancing doxorubicin anticancer activity with a novel polymeric platform photoreleasing nitric oxide

Sodano, Federica, Cavanagh, Robert J., Pearce, Amanda K., Lazzarato, Loretta, Rolando, Barbara, Fraix, Aurore, Abelha, Thais F., Vasey, Catherine E., Alexander, Cameron, Taresco, Vincenzo, Sortino, Sa

Journal:

Biomaterials Science

Year:

2020

File:

PDF, 1.96 MB

2020

32

Synthesis, chiral HPLC resolution and configuration assignment of 1-phenylglyceryl trinitrate stereomers

Konstantin Chegaev, Loretta Lazzarato, Gian Cesare Tron, Domenica Marabello, Antonella Di Stilo, Clara Cena, Roberta Fruttero, Alberto Gasco, Nicolas Vanthuyne, Christian Roussel

Journal:

Year:

2006

Language:

english

File:

PDF, 157 KB

english, 2006

33

Structure–Antioxidant Activity Relationships in a Series of NO-Donor Phenols

Paolo Tosco, Elisabetta Marini, Barbara Rolando, Loretta Lazzarato, Clara Cena, Massimo Bertinaria, Roberta Fruttero, Marianne Reist, Pierre-Alain Carrupt, Alberto Gasco

Journal:

Year:

2008

Language:

english

File:

PDF, 325 KB

english, 2008

34

NO-donor melatonin derivatives: synthesis and in vitro pharmacological characterization

Konstantin Chegaev, Loretta Lazzarato, Barbara Rolando, Elisabetta Marini, Paolo Tosco, Clara Cena, Roberta Fruttero, Francesca Bertolini, Marianne Reist, Pierre-Alain Carrupt, Valeria Lucini, Franco

Journal:

Journal of Pineal Research

Year:

2007

Language:

english

File:

PDF, 729 KB

english, 2007

35

Synthesis and biological activity of furoxan derivatives against Mycobacterium tuberculosis

Fernandes, Guilherme Felipe dos Santos, de Souza, Paula Carolina, Marino, Leonardo Biancolino, Chegaev, Konstantin, Guglielmo, Stefano, Lazzarato, Loretta, Fruttero, Roberta, Chin, Chung Man, Pavan, F

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.28 MB

english, 2016

36

Antiproliferative effect of furoxans in smooth muscle cells: Proteomic studies to unravel their mechanism of action

Arnaboldi, Lorenzo, Lombardi, Matteo, Sinelli, Matteo, Rolando, Barbara, Lazzarato, Loretta, Granata, Agnese, Gasco, Alberto, Fruttero, Roberta, Corsini, Alberto

Journal:

Atherosclerosis

Year:

2017

Language:

english

File:

PDF, 49 KB

english, 2017

37

Water-Soluble Nitric-Oxide-Releasing Acetylsalicylic Acid (ASA) Prodrugs

Rolando, Barbara, Lazzarato, Loretta, Donnola, Monica, Marini, Elisabetta, Joseph, Sony, Morini, Giuseppina, Pozzoli, Cristina, Fruttero, Roberta, Gasco, Alberto

Journal:

Year:

2013

Language:

english

File:

PDF, 500 KB

english, 2013

38

Doxorubicin-antioxidant co-drugs

Chegaev, Konstantin, Riganti, Chiara, Rolando, Barbara, Lazzarato, Loretta, Gazzano, Elena, Guglielmo, Stefano, Ghigo, Dario, Fruttero, Roberta, Gasco, Alberto

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 408 KB

english, 2013

39

A Potent and Selective P-gp Modulator for Altering Multidrug Resistance Due to Pump Overexpression

Guglielmo, Stefano, Contino, Marialessandra, Lazzarato, Loretta, Perrone, Maria Grazia, Blangetti, Marco, Fruttero, Roberta, Colabufo, Nicola Antonio

Journal:

Year:

2016

Language:

english

File:

PDF, 563 KB

english, 2016

40

Combination of PDT and NOPDT with a Tailored BODIPY Derivative

Lazzarato, Loretta, Gazzano, Elena, Blangetti, Marco, Fraix, Aurore, Sodano, Federica, Picone, Giulia Maria, Fruttero, Roberta, Gasco, Alberto, Riganti, Chiara, Sortino, Salvatore

Journal:

Year:

2019

Language:

english

File:

PDF, 1.96 MB

english, 2019

41

Synthesis and preliminary pharmacological characterisation of a new class of nitrogen-containing bisphosphonates (N-BPs)

Marco L. Lolli, Barbara Rolando, Paolo Tosco, Shilpi Chaurasia, Antonella Di Stilo, Loretta Lazzarato, Eva Gorassini, Riccardo Ferracini, Simonetta Oliaro-Bosso, Roberta Fruttero, Alberto Gasco

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 673 KB

english, 2010

42

Mitochondrial Delivery of Phenol Substructure Triggers Mitochondrial Depolarization and Apoptosis of Cancer Cells

Gazzano, Elena, Lazzarato, Loretta, Rolando, Barbara, Kopecka, Joanna, Guglielmo, Stefano, Costamagna, Costanzo, Chegaev, Konstantin, Riganti, Chiara

Journal:

Frontiers in Pharmacology

Year:

2018

Language:

english

File:

PDF, 5.47 MB

english, 2018

43

Novel antioxidant agents deriving from molecular combination of Vitamin C and NO-donor moieties

Clara Cena, Konstantin Chegaev, Silvia Balbo, Loretta Lazzarato, Barbara Rolando, Marta Giorgis, Elisabetta Marini, Roberta Fruttero, Alberto Gasco

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 188 KB

english, 2008

44

Antiinflammatory, Gastrosparing, and Antiplatelet Properties of New NO-Donor Esters of Aspirin

Cena, Clara, Lolli, Marco L., Lazzarato, Loretta, Guaita, Elena, Morini, Giuseppina, Coruzzi, Gabriella, McElroy, Stuart P., Megson, Ian L., Fruttero, Roberta, Gasco, Alberto

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 147 KB

english, 2003

45

gem -Dinitroalkyl Benzenes: A Novel Class of IOP-Lowering Agents for the Treatment of Ocular Hypertension

Blangetti, Marco, Rolando, Barbara, Marini, Elisabetta, Chegaev, Konstantin, Guglielmo, Stefano, Lazzarato, Loretta, Lucarini, Laura, Masini, Emanuela, Fruttero, Roberta

Journal:

ACS Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 747 KB

english, 2017

46

DNAâtargeted NO release photoregulated by green light

Sortino, Salvatore, Parisi, Cristina, Fraix, Aurore, Guglielmo, Stefano, Spyrakis, Francesca, Rolando, Barbara, Lazzarato, Loretta, Fruttero, Roberta, Gasco, Alberto

Journal:

Chemistry (Weinheim an der Bergstrasse, Germany)

Year:

2020

File:

PDF, 1.66 MB

2020

47

Fluorescent Nitric Oxide Photodonors Based on BODIPY and Rhodamine Antennae

Parisi, Cristina, Failla, Mariacristina, Fraix, Aurore, Rolando, Barbara, Gianquinto, Eleonora, Spyrakis, Francesca, Gazzano, Elena, Riganti, Chiara, Lazzarato, Loretta, Fruttero, Roberta, Gasco, Albe

Journal:

Chemistry - A European Journal

Year:

2019

File:

PDF, 3.14 MB

2019

48

Searching for New NO-Donor Aspirin-like Molecules: A New Class of Nitrooxy-acyl Derivatives of Salicylic Acid †

Lazzarato, Loretta, Donnola, Monica, Rolando, Barbara, Marini, Elisabetta, Cena, Clara, Coruzzi, Gabriella, Guaita, Elena, Morini, Giuseppina, Fruttero, Roberta, Gasco, Alberto, Biondi, Stefano, Ongin

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 267 KB

english, 2008

49

Synthesis and Biological Evaluation of the First Example of NO-Donor Histone Deacetylase Inhibitor

Borretto, Emily, Lazzarato, Loretta, Spallotta, Francesco, Cencioni, Chiara, D’Alessandra, Yuri, Gaetano, Carlo, Fruttero, Roberta, Gasco, Alberto

Journal:

ACS Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1.86 MB

english, 2013

50

A Nitric Oxide-Donor Furoxan Moiety Improves the Efficacy of Edaravone against Early Renal Dysfunction and Injury Evoked by Ischemia/Reperfusion

Chiazza, Fausto, Chegaev, Konstantin, Rogazzo, Mara, Cutrin, Juan C., Benetti, Elisa, Lazzarato, Loretta, Fruttero, Roberta, Collino, Massimo

Journal:

Oxidative Medicine & Cellular Longevity

Year:

2015

Language:

english

File:

PDF, 2.78 MB

english, 2015

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